Long acting injections and implants

  • 557 Pages
  • 2.50 MB
  • 9303 Downloads
  • English
by
Springer , New York
Drugs, Drug delivery systems, Administr
StatementJeremy C. Wright, Diane J. Burgess, editors
SeriesAdvances in delivery science and technology, Advances in delivery science and technology
Classifications
LC ClassificationsRS199.5 .L66 2012
The Physical Object
Paginationxv, 557 p. :
ID Numbers
Open LibraryOL25275807M
ISBN 10146140553X
ISBN 139781461405535, 9781461405542
LC Control Number2011937763
OCLC/WorldCa781712241

An intriguing variety of technologies have been developed Long acting injections and implants book provide long acting injections and implants. Many considerations need to go into the design of these systems in order to translate a concept from the lab bench to actual therapy for a patient.

Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.

An intriguing variety of technologies have been developed to provide long acting injections and implants.

Download Long acting injections and implants EPUB

Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo.

This chapter provides an overview of the area of long acting injections and implants, summarizing the contents of the book. As appropriate, the reader is directed to the relevant chapters. Do you. from book Long Acting Injections and Implants (pp) Long Acting Injections and Implants.

Chapter January Long Acting Injections and Implants (Advances in Delivery Science and Technology): Medicine & Health Science Books @ Topics covered in Long Acting Injections and Implants include the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in Format: Hardcover.

Long Acting Injections and Implants - Ebook written by Jeremy C. Wright, Diane J. Burgess. Read this book using Google Play Books app on your PC, android, iOS devices.

Download for offline reading, highlight, bookmark or take notes while you read Long Acting Injections and Implants.5/5(1). This book surveys the field of long acting injections and implants, which improve therapy, enhance patient compliance, and enhance dosing convenience. Topics include the historical development of drugs and diseases, and clinical applications for long acting injections and implants.

An intriguing variety of technologies have been developed to provide long acting injections and implants. Many considerations need to go into the design of these systems in order to translate a concept from the lab bench to actual therapy for a patient.

This book surveys and summarizes the : Springer New York. Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.

¡This book surveys and summarizes the field.¡ Topics covered in Long Acting. projects on long- acting injectables and implants including nine grants and five contracts as well as one internal collaboration.

The focus of these projects are: 1) to explore biorelevant in. Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.

An intriguing variety of technologies have been developed to provide long acting injections and implants. Many considerations. Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.

The long acting injections and implants that we provide for you will be ultimate to give preference. This reading book is your chosen book to accompany you when in your free time, in your lonely. This kind of book can help you to heal the lonely and get or add the inspirations to be more inoperative.

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Brand: Springer New York. Buy the Paperback Book Long Acting Injections and Implants by Jeremy C. Wright atCanada's largest bookstore. Free shipping and pickup in store on eligible orders. Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability.

An intriguing variety of technologies have been developed to provide long acting injections. Long acting injections and implants have been developed for controlled drug delivery to improve therapeutic effects, decrease dosing frequency, and also avoid potential drug toxicity.

Many pharmaceutical agents, such as biomacromolecules (e.g. peptides, proteins and gene therapeutics), drugs with poor bioavailability, and drugs for local Cited by: 4. Long-acting injectables (LAIs) and implants are designed to release a drug at a controlled rate for a specic duration and thereby achieve therapeutic drug concentrations for a prolonged period.

This chapter describes a variety of LAIs and implant platforms that are currently commercially available, or at an advanced stage of development. Abstract. This chapter provides an overview of the area of long acting injections and implants, summarizing the contents of the book.

As appropriate, the reader is directed to the relevant by: 6. Jeremy C. Wright is the author of Long Acting Injections and Implants ( avg rating, 0 ratings, 0 reviews, published ).

E-BOOK EXCERPT. Long acting injections and implants improve therapy, enhance patient compliance, improve dosing convenience, and are the most appropriate formulation choice for drugs that undergo extensive first pass metabolism or that exhibit poor oral bioavailability. Sustained release implants usually provide a longer term delivery duration than long acting injections and can be categorized into bioerodible systems (rods and cylinders) and implantable devices.

This chapter reviews biomolecules currently marketed or in clinical trials, utilizing long acting parenteral technology or sustained/controlled Cited by: 5.

Long-acting preparations can be classified variously-depending on the type of formulation used, such as depot injections, implants, patches; depending on what purpose the preparation is used for, such as detoxification, substitution, or abstinence promotion; depending on the target drug of abuse-and so on.

Antipsychotic long-acting injections (LAIs) were introduced in the s to improve treatment adherence in schizophrenia. Subsequently, first-generation antipsychotic LAIs became widely used in many countries.

Recently there has been a resurgence of interest in LAIs that partly reflects the introduction of several second-generation antipsychotic LAIs. FDA Panel Recommends Long-Acting Implant For Opioid Addiction: Shots - Health News A long-acting implant has gained approval from an FDA advisory committee.

It could soon become the latest on a. This review focuses on the current status and explores long-acting injectables with special attention to marketed products. Injectable routes, types of long-acting injectables (i.e., oil-based injections, injectable drug suspensions, injectable microspheres, and injectable in situ systems), drugs and polymers for depot injections, commercially available depot injections.

antipsychotic (both first generation and second generation) long-acting injections (LAIs) and typical and atypical oral antipsychotics, in terms of clinical outcomes. A systematic review of the literature has been performed.

A total of 71 papers were selected for this article.

Description Long acting injections and implants EPUB

Results are variable, mainly owing to methodological by: 9. Long Acting Injections and Implants includes the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots.

History of long acting injectable formulations Penicillin + probenicid Important in prolonging action of penicillin at time of short supply Probenicid blocks renal tubular secretion of penicillin NPH (Neutral protamine Hagedorn) insulin Insulin formulated with protamine derived from herring or salmon milt Protamine binds and precipitates proteinsFile Size: KB.

Antipsychotic long-acting injections. Oxford: Oxford University Press; 35 Advice on prescribing long-acting injections of antipsychotic drugs • For FGAs, give a test dose. For SGAs, test doses are not required (less propensity to cause EPS and aqueous base not known to be allergenic).

• Begin with the lowest therapeutic dose.Book Chapters. M. Kastellorizios, N. Tipnis, D.J. Burgess. Foreign body reaction to subcutaneous implants.

Details Long acting injections and implants FB2

(). In vitro Drug Release Testing and In Vivo/In Vitro Correlation for Long Acting Implants and Injections. In "Long acting injections and implants”. Eds. J. Wright and D.J.

: Gowtham Yenduri.